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Testosterone Cypionate Injectable Solution
2016-08-24 17:08:17 Highlights for Testosterone Cypionate
Injectable Solution
1
Testosterone cypionate is used to treat symptoms of hypogonadism in males. In this condition, males don't produce enough of the sex hormone testosterone.
2
This drug comes in the form of an injectable solution given into your muscle. You can give this medication to yourself at home after your doctor shows you how to give yourself an injection.
3
Testosterone cypionate is available as a brand-name drug called Depo-testosterone. It’s also available as a generic drug.
4
The more common side effects of this drug include acne, pain and swelling at the injection site, hair growth, breast enlargement, more frequent erections, erections that last longer than normal, decreased sperm count (when this drug is used at high doses), mood swings, and headaches.
5
In some cases, testosterone cypionate can cause serious side effects. These can include heart attack, stroke, enlargement of your prostate gland, increased risk of prostate cancer, liver problems, blood clots in your lungs and deep veins in your legs, and a significant increase in your red blood cell count.
IMPORTANT INFORMATION
Heart effects
Heart effects See Details
Liver problems
Liver problems See Details
Prostate problems in seniors
Prostate problems in seniors See Details
Blood clots
Blood clots See Details
What is testosterone cypionate?
Testosterone cypionate is a controlled prescription drug. It’s available as an injectable solution given into the muscle (intramuscular). Testosterone cypionate is a self-injectable drug.
Testosterone cypionate is available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version. Talk to your doctor to see if the generic version will work for you.
Why it's used
Testosterone cypionate is used to treat symptoms of hypogonadism in males. In this condition, males don't produce enough of the sex hormone testosterone.
More Details
How it works
Testosterone cypionate belongs to a class of drugs called androgens. A class of drugs is a group of medications that work in a similar way.
More Details
SECTION 2 of 5
Testosterone Cypionate Side Effects
Injectable Solution
MORE COMMON SIDE EFFECTS
The more common side effects of testosterone cypionate can include:
acne
pain and swelling at injection site
hair growth
gynecomastia (breast enlargement)
more frequent erections
erections that last longer than normal
decrease in sperm count when the drug is used at high doses
mood swings
headache
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
SERIOUS SIDE EFFECTS
Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Heart attack. Symptoms can include:
chest pain
shortness of breath
discomfort in your upper body
Stroke. Symptoms can include:
weakness in one part or side of your body
slurred speech
Enlargement of your prostate gland. Symptoms can include:
frequent or urgent need to urinate
nocturia (needing to urinate more often at night)
trouble starting urination
weak urine stream or a stream that stops and starts
dribbling at the end of urination
straining while urinating
not being able to completely empty your bladder
Prostate cancer. Your doctor should check for prostate cancer or any prostate problems before starting and during treatment with this drug, especially if you’re 65 years or older.
Liver problems. Symptoms can include:
nausea
vomiting
stomach pain and swelling
swelling in your legs and ankles
bruising more easily than normal
pale-colored stool
unusual or unexplained tiredness
loss of appetite
dark-colored urine
yellowing of your skin or the whites of your eyes
Venous thromboembolism (blood clots in your lungs and deep veins of your legs). Symptoms can include:
swelling of your leg
pain in your leg
shortness of breath
chest pain or discomfort that gets worse when you take a deep breath or when you cough
feeling lightheaded or dizzy, or fainting
fast pulse
coughing up blood
Polycythemia (increase in your red blood cell count). Symptoms can include:
reddening in your face
headaches
confusion
stroke
blood clots
tiredness
decrease in mental alertness
Pharmacist's Advice
Mary Lynn Moody, RPh, BSPharm
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy
Testosterone cypionate doesn’t cause drowsiness.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
SECTION 3 of 5
Testosterone Cypionate May Interact with Other Medications
Injectable Solution
Testosterone cypionate can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Medications that might interact with this drug
Interactions that increase your risk of side effects
Side effects from other drugs: Taking testosterone cypionate with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:
Insulin and oral diabetes drugs, such as nateglinide, pioglitazone, repaglinide, rosiglitazone, metformin, glimepiride, glipizide, sitagliptin, saxagliptin, linagliptin, exenatide and liraglutide. Taking these drugs together may cause a significant decrease in your blood sugar levels. Your doctor may decrease the dose of your diabetes drugs. You may need to monitor your blood sugar levels closely while taking these drugs together.
Oral blood thinners, such as warfarin. Taking these drugs together may increase your risk of bleeding. Your doctor will monitor you closely if you take these drugs together.
Corticosteroids and adrenocorticotropic hormone. Taking these drugs with testosterone cypionate puts you at a higher risk of edema (fluid build-up). Your doctor should monitor you closely for fluid build-up if you take these drugs together, especially if you have heart or liver problems.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Testosterone cypionate warnings
liver problems
People with liver problems
This medication can cause liver damage. This may lead to serious liver disease. If you have liver disease, this drug may also cause salt and water retention. This may make your liver disease worse.
heart problems
People with heart problems
If you have heart disease, this drug may cause salt and water retention. Both the medication and the salt and water retention can make your conditions worse. If you have a history of heart attack or heart disease, ask your doctor whether this drug is safe for you.
kidney problems
People with kidney problems
If you have kidney problems or a history of kidney disease, this drug may cause salt and water retention. Both the medication and salt and water retention can make your conditions worse.
breast cancer
People with breast cancer
You shouldn’t take this drug if you’re a man with breast cancer. This medication may make your disease worse.
prostate cancer
People with prostate cancer
You shouldn’t take this drug if you have prostate cancer. Testosterone cypionate may make your disease worse.
sleep apnea
People with sleep apnea (problems breathing while sleeping)
If you have sleep apnea, ask your doctor whether this drug is safe for you. This medication may make this condition worse. You may wake up more often at night, which may cause you to be more tired during the day.
polycythemia
People with polycythemia (elevated red blood cell count)
This drug may significantly increase your red blood cell count and make your condition worse. You shouldn’t use this drug if your hematocrit is above 54%.
high cholesterol levels
People with high cholesterol levels
This drug may increase your cholesterol levels. High cholesterol levels may increase your risk of heart or blood vessel problems. Your doctor will check your cholesterol levels while you take this medication.
diabetes
People with diabetes
This drug may cause a significant decrease in your blood sugar levels. Your doctor may lower the dose of your diabetes drugs. You may also need to monitor your blood sugar levels closely.
blood clots
People with blood clots
This drug may increase your risk of developing blood clots in your lungs or in the deep veins of your legs, especially if you already had or have blood clots.
Pregnant women
Pregnant women
Testosterone cypionate is a category X pregnancy drug. Category X drugs should never be used during pregnancy.
This drug should only be used in males.
seniors
For seniors
This drug shouldn’t be used to treat age-related decreases in testosterone. There isn’t enough information from clinical trials in seniors ages 65 years and older to support the use of this drug for a long period of time.
If you’re older than 65 years, you may be at a higher risk of heart disease, prostate cancer, and enlarged prostate while taking this drug.
children
For children
It hasn’t been confirmed that testosterone cypionate is safe and effective for use in children younger than 12 years.
Testosterone cypionate may affect bone growth in children. This drug can cause bones to mature more quickly than normal without causing an increase in height. This can result in a shorter adult height. Your child's doctor will check their growth regularly.
call the doctor
When to call the doctor
Call your doctor if your symptoms of low testosterone aren’t improving or are getting worse after you’ve been taking the drug for 3–6 months.
allergies
Allergies
Testosterone cypionate can cause a severe allergic reaction. Symptoms can include:
trouble breathing
swelling of your throat or tongue
If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room.
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
SECTION 4 of 5
How to Take Testosterone Cypionate (Dosage)
Injectable Solution
All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:
your age
the condition being treated
how severe your condition is
other medical conditions you have
how you react to the first dose
What are you taking this medication for?
Primary hypogonadism
Generic: testosterone cypionate
Form: Injectable solutionStrengths: 100 mg/mL, 200 mg/mL
Brand: Depo-testosterone
Form: Injectable solutionStrengths: 100 mg/mL, 200 mg/mL
Adult dosage (ages 18 years and older)
Typical starting dose: Your dose depends on your age and diagnosis. Your doctor will decide a dosage that’s right for you based on your needs. In general, the dose is 50–400 mg injected into your muscle every 2–4 weeks.
Dose increases: Your doctor may adjust your dose based on your testosterone blood levels, response to treatment, and side effects.
Maximum dose: 400 mg injected into your muscle every 2 weeks.
Child dosage (ages 12–17 years)
Typical starting dose: Your dose depends on your age and diagnosis. Your doctor will decide a dosage that’s right for you based on your needs. In general, the dose is 50–400 mg injected into your muscle every 2–4 weeks.
Dose increases: Your doctor may adjust your dose based on your testosterone blood levels, response to treatment, and side effects.
Maximum dose: 400 mg injected into your muscle every 2 weeks.
Child dosage (ages 0–11 years)
It hasn’t been confirmed that testosterone cypionate is safe and effective for use in people younger than 12 years.
Hypogonadotropic hypogonadism
Generic: testosterone cypionate
Form: Injectable solutionStrengths: 100 mg/mL, 200 mg/mL
Brand: Depo-testosterone
Form: Injectable solutionStrengths: 100 mg/mL, 200 mg/mL
Adult dosage (ages 18 years and older)
Typical starting dose: Your dose depends on your age and diagnosis. Your doctor will decide a dosage that’s right for you based on your needs. In general, the dose is 50–400 mg injected into your muscle every 2–4 weeks.
Dose increases: Your doctor may adjust your dose based on your testosterone blood levels, response to treatment, and side effects.
Maximum dose: 400 mg injected into your muscle every 2 weeks.
Child dosage (ages 12–17 years)
Typical starting dose: Your dose depends on your age and diagnosis. Your doctor will decide a dosage that’s right for you based on your needs. In general, the dose is 50–400 mg injected into your muscle every 2–4 weeks.
Dose increases: Your doctor may adjust your dose based on your testosterone blood levels, response to treatment, and side effects.
Maximum dose: 400 mg injected into your muscle every 2 weeks.
Child dosage (ages 0–11 years)
It hasn’t been confirmed that testosterone cypionate is safe and effective for use in people younger than 12 years.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Mary Lynn Moody, RPh, BSPharm
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy
Testosterone cypionate comes with serious risks if you don’t take it as prescribed.
If you stop taking the drug suddenly or don’t take it at all
Your medication may not work as well. For this drug to work well, a certain amount needs to be in your body at all times. If you don’t take this drug, you may still have symptoms of low testosterone. These include mood changes, poor concentration, erectile dysfunction (trouble getting or keeping an erection), low sex drive, reduced growth of penis and testicles, gynecomastia (breast growth), loss of body hair and muscle mass, anemia, and osteoporosis.
If you miss doses or don’t take the drug on schedule
Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.
If you take too much
You could have dangerous levels of the drug in your body. Symptoms may include:
acne
pain and swelling at injection site
hair growth
gynecomastia (breast enlargement)
more frequent erections
erections that last longer than normal
decrease in sperm count
mood swings
headache
If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room right away.
What to do if you miss a dose
Take your dose as soon as you remember. Call your doctor. Tell them how long it’s been since you last injected testosterone cypionate. They will help you set up a new dosing schedule. Never try to catch up by taking two doses at once. This could result in dangerous side effects.
How to tell if the drug is working
Your symptoms of low testosterone should improve and may go away. These include mood changes, poor concentration, erectile dysfunction (trouble getting or keeping an erection), low sex drive, reduced growth of penis and testicles, gynecomastia (breast growth), loss of body hair and muscle mass, anemia, and osteoporosis.
Testosterone cypionate is used for long-term treatment.
Important considerations for taking testosterone cypionate
timing
Take this drug at the time(s) recommended by your doctor
storage
Store this drug carefully
See Details medication is refillable
A prescription for this medication is refillable
See Details Travel
Travel
See Details Self-management
Self-management
See Details Clinical monitoring
Clinical monitoring
See Details not usually stocked
Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead
Hidden costs
Hidden costs
See Details prior authorization required
Insurance
See Details
Are there any alternatives?
There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.
SECTION 5 of 5
How Much Does Testosterone Cypionate Cost?
Injectable Solution
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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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